
Atorvastatin belongs to
the group of medicines called 3-hydroxy-3-methylglutaryl coenzyme
A (HMG-CoA) reductase inhibitors. It works by blocking an enzyme
that is needed by the body to make cholesterol thereby reducing
the amount of cholesterol in the blood.
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About Atorvastatin (Lipitor):
Product Type: Cholesterol
Brand name: Atorvastatin
Generic name: Lipitor What is the most important information I should
know about Atorvastatin? • Rare cases of muscle problems and liver
problems have been associated with the use of Atorvastatin and other
similar medicines. Contact your doctor immediately if you experience
unexplained muscle pain tenderness or weakness especially if accompanied
by a fever or flulike symptoms or yellowing of the skin or eyes
abdominal pain unexplained fatigue dark colored urine or pale colored
stools. These may be early symptoms of muscle or liver problems.
• Do not take Atorvastatin without first talking to your doctor
if you have liver disease. • Alcohol and Atorvastatin can both be
damaging to the liver. Alcohol should be used only in moderation.
Discuss the use of alcohol with your doctor so that the potential
for liver problems can be determined. • Do not take Atorvastatin
if you are pregnant could become pregnant during treatment or if
you are breast-feeding a baby. What is Atorvastatin? • Atorvastatin
is an HMG CoA reductase inhibitor. Atorvastatin blocks the production
of cholesterol (a type of fat) in the body. • Atorvastatin is used
to reduce the amounts of LDL (bad) cholesterol total cholesterol
triglycerides (another type of fat) and apolipoprotein B (a protein
needed to make cholesterol) in your blood. Atorvastatin is also
used to increase the level of HDL (good) cholesterol in your blood.
These actions are important in reducing the risk of hardening of
the arteries which can lead to heart attacks stroke and peripheral
vascular disease. • Atorvastatin may also be used for purposes other
than those listed in this medication guide. What should I discuss
with my healthcare provider before taking Atorvastatin? • Do not
take Atorvastatin without first talking to your doctor if you have
liver disease. • Before taking Atorvastatin tell your doctor if
you drink alcoholic beverages have a chronic muscular disease require
major surgery or have a blood disorder. • You may not be able to
take Atorvastatin or you may require a dosage adjustment or special
monitoring during treatment if you have any of the conditions listed
above. • Atorvastatin is in the FDA pregnancy category X. This means
that Atorvastatin is known to cause birth defects if it is taken
during pregnancy. Do not take Atorvastatin if you are pregnant or
could become pregnant during treatment. • It is not known whether
Atorvastatin passes into breast milk. Do not take this medication
without first talking to your doctor if you are breast-feeding a
baby. How should I take Atorvastatin? • Take Atorvastatin exactly
as directed by your doctor. If you do not understand these directions
ask your pharmacist nurse or doctor to explain them to you. • Take
each dose with a full glass of water. • Atorvastatin can be taken
with or without food. • Atorvastatin is usually taken once a day.
Try to take your dose at the same time each day. Follow your doctor's
instructions. • Your doctor may want to monitor your liver function
with blood tests before starting treatment with Atorvastatin at
twelve weeks after both the start of your treatment and any increase
in dose and periodically (every 6 months) thereafter. Depending
on the results of these tests your doctor can determine how much
monitoring you will require. • Grapefruit and grapefruit juice may
interact with Atorvastatin. The interaction could lead to potentially
dangerous effects. Discuss the use of grapefruit and grapefruit
juice with your doctor. Do not increase or decrease the amount of
grapefruit products in your diet without first talking to your doctor.
• Eat a low-fat low-cholesterol diet. To realize beneficial effects
from Atorvastatin avoid fatty high-cholesterol foods. • It is important
to take Atorvastatin regularly to get the most benefit. • Do not
stop taking Atorvastatin without first talking to your doctor. Atorvastatin
may need to be taken on a long-term basis for the treatment of high
cholesterol. • Your doctor may want you to have blood tests or other
medical evaluations during treatment with Atorvastatin to monitor
progress and side effects. • Store Atorvastatin at room temperature
away from moisture and heat. What happens if I miss a dose? • Take
the missed dose as soon as you remember. However if it is almost
time for the next dose skip the missed dose and take only the next
regularly scheduled dose. Do not take a double dose of this medication.
What happens if I overdose? • Seek emergency medical attention if
an overdose is suspected. • The symptoms of an Atorvastatin overdose
are not known. What should I avoid while taking Atorvastatin? •
Alcohol and Atorvastatin can both be damaging to the liver. Alcohol
should be used only in moderation. Discuss the use of alcohol with
your doctor so that the potential for liver problems can be determined.
• Grapefruit and grapefruit juice may interact with Atorvastatin.
The interaction could lead to potentially dangerous effects. Discuss
the use of grapefruit and grapefruit juice with your doctor. Do
not increase or decrease the amount of grapefruit products in your
diet without first talking to your doctor. What are the possible
side effects of Atorvastatin? • Rare cases of muscle problems and
liver problems have been associated with the use of Atorvastatin
and other similar medicines. Contact your doctor immediately if
you experience unexplained muscle pain tenderness or weakness especially
if accompanied by a fever or flulike symptoms or yellowing of the
skin or eyes abdominal pain unexplained fatigue dark colored urine
or pale colored stools. These may be early symptoms of muscle or
liver problems. • If you experience any of the following serious
side effects stop taking Atorvastatin and seek emergency medical
attention or contact your doctor immediately: an allergic reaction
(difficulty breathing; closing of the throat; swelling of the lips
tongue or face; or hives); decreased urine or rust-colored urine;
or blurred vision. • Other less serious side effects may be more
likely to occur. Continue to take Atorvastatin and talk to your
doctor if you experience headache; upset stomach or flatulence;
or a rash. • Side effects other than those listed here may also
occur. Talk to your doctor about any side effect that seems unusual
or that is especially bothersome. What other drugs will affect Atorvastatin?
• Do not take Atorvastatin without first talking to your doctor
if you are taking any of the following medicines: cyclosporine (Sandimmune
Neoral); gemfibrozil (Lopid) clofibrate (Atromid-S) or fenofibrate
(Tricor); niacin (Nicolar Nicobid Slo-Niacin others); erythromycin
(E-Mycin E.E.S. Ery-Tab others) or clarithromycin (Biaxin); cholestyramine
(Questran) or colestipol (Colestid); hormonal birth control (pills
patches or implants); or an antifungal medication such as itraconazole
(Sporanox) fluconazole (Diflucan) or ketoconazole (Nizoral). • You
may not be able to take Atorvastatin or you may require a dosage
adjustment or special monitoring during treatment if you are taking
any of the medicines listed above. • Drugs other than those listed
here may also interact with Atorvastatin. Talk to your doctor and
pharmacist before taking any prescription or over-the-counter medicines
including vitamins minerals and herbal products.
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Prescription Drug:
Prescription News : The number of medical prescriptions issued outside hospitals in England has gone up by 70 per cent in the last decade, according to figures from the NHS Information Centre. At the same time the average number of prescriptions per person has gone from 11.2 to 17.8 and the overall spend on prescription drugs went up from £5.59bn to £8.83bn, roughly 10 per cent of the NHS's budget.
The figures show that there were 552m prescriptions in 2000 but 927m in 2010, with the majority of medicines prescribed being for heart disease. The increase is said to be down to both an increase in heart disease and more effective drugs coming on to the market to treat it. However, there were fears that the increase may be down to GPs taking the easy option with patients where consultation time is restricted.
The care services minister Paul Burstow said: "[This] big rise in prescribing ... largely reflects the impact of a growing and ageing population, as well as an increase in the prescribing of preventative medicines, such as low cost statins, for cardiovascular diseases."
Agreeing with the government, the British Medical Association issued this statement: "A key reason for the increase in the number of prescriptions given to patients is that the number of medicines available has increased substantially in the past decade. This relates particularly to important preventative treatments, such as those that lower cholesterol."


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